Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9BZX2 / UCK2_HUMAN
Protein Name Uridine-cytidine kinase 2
Gene Name Name: UCK2
Organism Homo sapiens (Human)

DAG View
PRO Name uridine-cytidine kinase 2 (human)
Definition A uridine-cytidine kinase 2 that is encoded in the genome of human.
Short Label hUCK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9BZX2 (UCK2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K33 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T106 O-Glycosylation GlyGen 23301498, 29351928
T157 Phosphorylation PhosphoSitePlus
R162 Methylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
S254 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
Site PTM Type PTM Enzyme Score Source PMID
S254 Phosphorylation HPRD 19651622, 18691976, 17081983, ...20068231
S256 Phosphorylation HPRD 17081983
S258 Phosphorylation HPRD 19651622

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ tcga ]
K33 N33 Biomuta DOID:1324 / lung cancer [ cosmic ]
K39 * Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
K54 E54 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K99 N99 Biomuta DOID:363 / uterine cancer [ tcga ]
K202 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K202 T202 Biomuta DOID:363 / uterine cancer [ tcga ]
S258 C258 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]