iPTMnet Report for Q9BZX2 (UCK2)
Protein Information
| UniProt AC / UniProt ID | Q9BZX2 / UCK2_HUMAN |
| Protein Name | Uridine-cytidine kinase 2 |
| Gene Name | Name: UCK2 Synonyms:UMPK; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BZX2 |
| PRO Name | uridine-cytidine kinase 2 (human) |
| Definition | A uridine-cytidine kinase 2 that is encoded in the genome of human. |
| Short Label | hUCK2 |
| Category | organism-gene |
Q9BZX2 (UCK2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y51 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K75 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K99 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T106 | O-Glycosylation | score1 | GlyGen | 23301498, 29351928 | ||
| T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R162 | Methylation | score1 | PhosphoSitePlus | |||
| T200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S248 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S254 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 17081983 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | T2 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K33 | N33 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K39 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| Y51 | H51 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K99 | R99 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| T157 | I157 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| R162 | Q162 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K202 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K202 | T202 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S258 | C258 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View