iPTMnet Report for Q9BZR9 (TRIM8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZR9 / TRIM8_HUMAN
Protein Name E3 ubiquitin-protein ligase TRIM8
Gene Name Name: TRIM8
Synonyms:GERP,RNF27;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZR9
DAG View
PRO Name E3 ubiquitin-protein ligase TRIM8 (human)
Definition An E3 ubiquitin-protein ligase TRIM8 that is encoded in the genome of human.
Short Label hTRIM8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZR9 (TRIM8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S518 Phosphorylation IEDB 35494241


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K45 N45 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K229 R229 Biomuta DOID:4159 / skin cancer [ cosmic ]
K229 N229 Biomuta DOID:4159 / skin cancer [ cosmic ]
S321 Y321 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K339 Q339 Biomuta DOID:1324 / lung cancer [ cosmic ]
S371 G371 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S518 N518 Biomuta DOID:363 / uterine cancer [ cosmic ]