iPTMnet Report for Q9BZL6 (PRKD2)
Protein Information
UniProt AC / UniProt ID | Q9BZL6 / KPCD2_HUMAN |
Protein Name | Serine/threonine-protein kinase D2 |
Gene Name | Name: PRKD2 Synonyms:PKD2;ORFNames:HSPC187; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BZL6 |
PRO Name | serine/threonine-protein kinase D2 (human) |
Definition | A serine/threonine-protein kinase D2 that is encoded in the genome of human. |
Short Label | hPRKD2 |
Category | organism-gene |
Q9BZL6 (PRKD2) as Substrate
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y87 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 28428613 | ||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
T101 | Phosphorylation | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 16083285, 23186163, 18220336, ...17192257, 18669648 | ||
S198 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 16083285, 23186163 | ||
T199 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S200 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S203 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 21406692 | ||
S206 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19369195, 18669648, 23186163 | ||
T211 | Phosphorylation | score1 | PhosphoSitePlus | |||
S212 | Phosphorylation | score1 | PhosphoSitePlus | |||
S214 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569, 17192257 | ||
C217 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
T227 | Phosphorylation | score1 | PhosphoSitePlus | |||
S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
S241 | Phosphorylation | score1 | PhosphoSitePlus | |||
S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
S244 | Phosphorylation | P48730 (CSNK1D) , P49674 (CSNK1E) | score3 | PhosphoSitePlus UniProt | 17962809 | |
S245 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
S362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S374 | Phosphorylation | score1 | PhosphoSitePlus | |||
S375 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y378 | Phosphorylation | score1 | PhosphoSitePlus | |||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
T391 | Phosphorylation | score1 | PhosphoSitePlus | |||
T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
S395 | O-Glycosylation | score1 | GlyGen | 22564745, 35254053 | ||
S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
S396 | O-Glycosylation | score1 | GlyGen | 22564745, 35254053 | ||
S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
T398 | Phosphorylation | score1 | PhosphoSitePlus | |||
T412 | Phosphorylation | score1 | PhosphoSitePlus | |||
K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y438 | Phosphorylation | P29597 (TYK2) | score4 | neXtProt PhosphoSitePlus RLIMS-P UniProt | 28428613, 21865166, 15604256 | |
S518 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
S529 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 30784271 | ||
K572 | Acetylation | score1 | PhosphoSitePlus | |||
K580 | Acetylation | score1 | PhosphoSitePlus | |||
K580 | Ubiquitination | score1 | PhosphoSitePlus | |||
K584 | Acetylation | score1 | PhosphoSitePlus | |||
T589 | Phosphorylation | score1 | IEDB | 35494241 | ||
K590 | Ubiquitination | score1 | PhosphoSitePlus | |||
T619 | Phosphorylation | score1 | PhosphoSitePlus | |||
K643 | Ubiquitination | score1 | PhosphoSitePlus | |||
K676 | Ubiquitination | score1 | PhosphoSitePlus | |||
K692 | Ubiquitination | score1 | PhosphoSitePlus | |||
K705 | Ubiquitination | score1 | PhosphoSitePlus | |||
S706 | Phosphorylation | Q02156 (PRKCE) , P17252 (PRKCA) , P24723 (PRKCH) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 28428613, 12058027 | |
S710 | Phosphorylation | Q02156 (PRKCE) , P17252 (PRKCA) , P24723 (PRKCH) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 18691976, 28428613, 23186163, ...12058027, 19369195, 17192257, 18669648 | |
T714 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
Y717 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 19369195, 18669648, 28428613 | ||
S876 | Phosphorylation | P24723 (PRKCH) , Q9BZL6 (PRKD2) , P17252 (PRKCA) , Q02156 (PRKCE) , Q13563 (PKD2) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 18691976, 11062248, 12058027, ...19369195, 23562655, 30718593 |
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S197 | Phosphorylation | score0 | HPRD | 18691976, 16083285, 19651622, ...17322306, 18669648, 20166139 | ||
S198 | Phosphorylation | score0 | HPRD | 20166139, 18691976, 18669648, ...16083285, 20068231 | ||
T199 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 17081983, ...20068231 | ||
S200 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 17192257 | ||
S203 | Phosphorylation | score0 | HPRD | 18669648 | ||
S206 | Phosphorylation | score0 | HPRD | 18669648 | ||
S214 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18669648 | ||
S236 | Phosphorylation | score0 | HPRD | 18691976 | ||
S353 | Phosphorylation | score0 | HPRD | 18691976 | ||
S375 | Phosphorylation | score0 | HPRD | 18691976 | ||
S396 | Phosphorylation | score0 | HPRD | 18691976 | ||
S518 | Phosphorylation | score0 | HPRD | 18691976 | ||
S706 | Phosphorylation | score0 | HPRD | 18691976, 17192257 | ||
S710 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17192257 | ||
T714 | Phosphorylation | score0 | HPRD | 18669648 | ||
Y717 | Phosphorylation | score0 | HPRD | 18669648 | ||
S876 | Phosphorylation | Q9BZL6 (PRKD2) | score2 | HPRD | 18691976, 11062248 |
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S40 | Phosphorylation | score0 | HPRD | 17322306, 18691976, 18669648, ...20166139, 19651622 | ||
S41 | Phosphorylation | score0 | HPRD | 20166139, 18691976, 18669648, ...20068231 | ||
T42 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 17081983, ...20068231 | ||
S43 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 17192257 | ||
S46 | Phosphorylation | score0 | HPRD | 18669648 | ||
S49 | Phosphorylation | score0 | HPRD | 18669648 | ||
S57 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18669648 | ||
S79 | Phosphorylation | score0 | HPRD | 18691976 | ||
S196 | Phosphorylation | score0 | HPRD | 18691976 | ||
S218 | Phosphorylation | score0 | HPRD | 18691976 | ||
S239 | Phosphorylation | score0 | HPRD | 18691976 | ||
S361 | Phosphorylation | score0 | HPRD | 18691976 | ||
S549 | Phosphorylation | score0 | HPRD | 18691976, 17192257 | ||
S553 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17192257 | ||
T557 | Phosphorylation | score0 | HPRD | 18669648 | ||
Y560 | Phosphorylation | score0 | HPRD | 18669648 | ||
S719 | Phosphorylation | score0 | HPRD | 18691976 |
Q9BZL6 (PRKD2) as PTM Enzyme
Substrate | Site | Score | Source | PMID | |
---|---|---|---|---|---|
P16144-2 (ITGB4) | T1736 | score2 | PhosphoSitePlus | 26580203 | |
P17181 (IFNAR1) | S535 | score2 | neXtProt | 21865166 | |
P50552 (VASP) | S157 | score2 | PhosphoSitePlus | 26336132 | |
P50552 (VASP) | S239 | score2 | PhosphoSitePlus | 26336132 | |
P50552 (VASP) | S322 | score2 | PhosphoSitePlus | 26336132 | |
Q01105-2 (SET) | S171 | score3 | neXtProt PhosphoSitePlus | 23251465 | |
Q13563 (PKD2) | S801 | score2 | PhosphoSitePlus | 20881056 | |
Q13671 (RIN1) | S292 | score2 | PhosphoSitePlus | 21209314 | |
Q7KZI7 (MARK2) | S400 | score2 | PhosphoSitePlus | 19011111 | |
Q8WYL5 (SSH1) | S937 | score4 | PhosphoSitePlus Signor | 21525957, 19567672 | |
Q8WYL5 (SSH1) | S978 | score2 | PhosphoSitePlus | 19567672 | |
Q99828 (CIB1) | S78 | score2 | PhosphoSitePlus | 23503467 | |
Q9BST9 (RTKN) | S448 | score2 | neXtProt | 22228765 | |
Q9BZL6-1 (PRKD2) | S876 | score4 | HPRD PhosphoSitePlus Signor UniProt | 18691976, 11062248 | |
Q9UBF8-2 (PI4KB) | S294 | score4 | neXtProt PhosphoSitePlus Signor | 16912074, 16100512 | |
Q9UQL6 (HDAC5) | S498 | score3 | neXtProt PhosphoSitePlus | 16584705 |
PTM sites affected in variants
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