iPTMnet Report for Q9BZJ0 (CRNKL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZJ0 / CRNL1_HUMAN
Protein Name Crooked neck-like protein 1
Gene Name Name: CRNKL1
Synonyms:CRN;ORFNames:CGI-201,MSTP021;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZJ0
DAG View
PRO Name crooked neck-like protein 1 (human)
Definition A crooked neck-like protein 1 that is encoded in the genome of human.
Short Label hCRNKL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZJ0 (CRNKL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 22814378
T2 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K170 Sumoylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K229 Methylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
K381 Acetylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
Y438 Phosphorylation PhosphoSitePlus
R442 Methylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y514 Phosphorylation PhosphoSitePlus
T598 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
C625 Methylation IEDB 31844290
K631 Ubiquitination PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
K823 Acetylation PhosphoSitePlus
K823 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T598 Phosphorylation HPRD 20068231
S599 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T2 M2 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S141 Y141 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K170 N170 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y265 H265 Biomuta DOID:1319 / brain cancer [ cosmic ]
K388 N388 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y438 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K453 T453 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K453 I453 Biomuta DOID:4159 / skin cancer [ cosmic ]
K740 R740 Biomuta DOID:10534 / stomach cancer [ cosmic ]