iPTMnet Report for Q9BZI7 (UPF3B)
Protein Information
UniProt AC / UniProt ID | Q9BZI7 / REN3B_HUMAN |
Protein Name | Regulator of nonsense transcripts 3B |
Gene Name | Name: UPF3B Synonyms:RENT3B; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BZI7 |
PRO Name | regulator of nonsense transcripts 3B (human) |
Definition | A regulator of nonsense transcripts 3B that is encoded in the genome of human. |
Short Label | hUPF3B |
Category | organism-gene |
Q9BZI7 (UPF3B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y79 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y98 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y117 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y160 | Phosphorylation | score1 | PhosphoSitePlus | |||
K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y167 | Phosphorylation | score1 | PhosphoSitePlus | |||
T169 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
T175 | Phosphorylation | score1 | PhosphoSitePlus | |||
T177 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T180 | Phosphorylation | score1 | PhosphoSitePlus | |||
K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
T198 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
S310 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163 | ||
T320 | Phosphorylation | score1 | PhosphoSitePlus | |||
S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y352 | Phosphorylation | score1 | PhosphoSitePlus | |||
T399 | Phosphorylation | score1 | PhosphoSitePlus | |||
K406 | Acetylation | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
S415 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
K421 | Acetylation | score1 | PhosphoSitePlus | |||
R436 | Methylation | score1 | PhosphoSitePlus | |||
Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
R447 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
S458 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T23 | Phosphorylation | score0 | HPRD | 20068231 | ||
T169 | Phosphorylation | score0 | HPRD | 17322306, 18669648, 19664994, ... | ||
T177 | Phosphorylation | score0 | HPRD | 18669648 | ||
T197 | Phosphorylation | score0 | HPRD | 20068231 | ||
T198 | Phosphorylation | score0 | HPRD | 20068231 | ||
S310 | Phosphorylation | score0 | HPRD | 20068231, 18452278 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T23 | Phosphorylation | score0 | HPRD | 20068231 | ||
T169 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18212344, 19664994, 17322306, ... | ||
T177 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648 | ||
T197 | Phosphorylation | score0 | HPRD | 20068231 | ||
T198 | Phosphorylation | score0 | HPRD | 20068231 | ||
K267 | Acetylation | score1 | PhosphoSitePlus | |||
S297 | Phosphorylation | score0 | HPRD | 20068231, 18452278 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y117 | D117 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K162 | E162 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T198 | I198 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K267 | N267 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] | |
T399 | A399 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K406 | T406 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K421 | R421 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
R436 | H436 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
R447 | Q447 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] |