iPTMnet Report for Q9BZI7 (UPF3B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZI7 / REN3B_HUMAN
Protein Name Regulator of nonsense transcripts 3B
Gene Name Name: UPF3B
Synonyms:RENT3B;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZI7
DAG View
PRO Name regulator of nonsense transcripts 3B (human)
Definition A regulator of nonsense transcripts 3B that is encoded in the genome of human.
Short Label hUPF3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZI7 (UPF3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T15 Phosphorylation PhosphoSitePlus
T18 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
T169 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...19690332
T175 Phosphorylation PhosphoSitePlus
T177 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T180 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus   UniProt 20068231
K205 Ubiquitination PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
T320 Phosphorylation PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
K406 Acetylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
T419 Phosphorylation PhosphoSitePlus
K421 Acetylation PhosphoSitePlus
R436 Methylation PhosphoSitePlus
Y442 Phosphorylation PhosphoSitePlus
R447 Methylation PhosphoSitePlus   UniProt 24129315
S458 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T23 Phosphorylation HPRD 20068231
T169 Phosphorylation HPRD 17322306, 18669648, 19664994, ...18212344, 20068231
T177 Phosphorylation HPRD 18669648
T197 Phosphorylation HPRD 20068231
T198 Phosphorylation HPRD 20068231
S310 Phosphorylation HPRD 20068231, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T23 Phosphorylation HPRD 20068231
T169 Phosphorylation HPRD   PhosphoSitePlus 18212344, 19664994, 17322306, ...18669648, 20068231
T177 Phosphorylation HPRD   PhosphoSitePlus 18669648
T197 Phosphorylation HPRD 20068231
T198 Phosphorylation HPRD 20068231
K267 Acetylation PhosphoSitePlus
S297 Phosphorylation HPRD 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y117 D117 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K162 E162 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T198 I198 Biomuta DOID:4159 / skin cancer [ cosmic ]
K267 N267 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ]
T399 A399 Biomuta DOID:363 / uterine cancer [ icgc ]
K406 T406 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K421 R421 Biomuta DOID:363 / uterine cancer [ icgc ]
R436 H436 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
R447 Q447 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]