iPTMnet Report for Q9BZI1 (IRX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZI1 / IRX2_HUMAN
Protein Name Iroquois-class homeodomain protein IRX-2
Gene Name Name: IRX2
Synonyms:IRXA2;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZI1
DAG View
PRO Name iroquois-class homeodomain protein IRX-2 (human)
Definition An iroquois-class homeodomain protein IRX-2 that is encoded in the genome of human.
Short Label hIRX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZI1 (IRX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation P28482 (MAPK1) neXtProt 15133517
S64 Phosphorylation P28482 (MAPK1) neXtProt 15133517
S186 Phosphorylation PhosphoSitePlus   UniProt 21406692
S231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
S317 Phosphorylation P27361 (MAPK3) neXtProt   PhosphoSitePlus 15133517
S325 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S231 L231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 L233 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S254 L254 Biomuta DOID:10534 / stomach cancer [ cosmic ]