iPTMnet Report for Q9BZF9 (UACA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZF9 / UACA_HUMAN
Protein Name Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene Name Name: UACA
Synonyms:KIAA1561;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZF9
DAG View
PRO Name uveal autoantigen with coiled-coil domains and ankyrin repeats (human)
Definition A uveal autoantigen with coiled-coil domains and ankyrin repeats that is encoded in the genome of human.
Short Label hUACA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZF9 (UACA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K49 Ubiquitination PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K57 Acetylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
C116 Methylation IEDB 31844290
T169 Phosphorylation IEDB 35494241
T250 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K268 Acetylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
Y375 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
K493 Methylation PhosphoSitePlus
K504 Methylation PhosphoSitePlus
T518 Phosphorylation PhosphoSitePlus
Y553 Phosphorylation PhosphoSitePlus
K562 Acetylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
T706 O-Glycosylation GlyGen 30379171, 28411811, 28510447, ...34019948
Y723 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K730 Ubiquitination PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
Y922 Phosphorylation PhosphoSitePlus
Y953 Phosphorylation PhosphoSitePlus
Y985 Phosphorylation PhosphoSitePlus
T1013 Phosphorylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
K1035 Sumoylation PhosphoSitePlus
T1048 Phosphorylation PhosphoSitePlus
S1062 Phosphorylation PhosphoSitePlus
T1065 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
Y1079 Phosphorylation PhosphoSitePlus
S1123 Phosphorylation PhosphoSitePlus
S1206 Phosphorylation PhosphoSitePlus
K1212 Acetylation PhosphoSitePlus
K1216 Acetylation PhosphoSitePlus
K1228 Acetylation PhosphoSitePlus
S1234 Phosphorylation PhosphoSitePlus
S1281 Phosphorylation PhosphoSitePlus
S1339 Phosphorylation PhosphoSitePlus
S1353 Phosphorylation PhosphoSitePlus
T1358 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T434 Phosphorylation HPRD 20068231
S435 Phosphorylation HPRD 20068231
Y723 Phosphorylation HPRD 18083107
S793 Phosphorylation HPRD 20068231
T801 Phosphorylation HPRD 17322306, 18767875
T1065 Phosphorylation HPRD 15302935
Site PTM Type PTM Enzyme Score Source PMID
T421 Phosphorylation HPRD 20068231
S422 Phosphorylation HPRD 20068231
Y710 Phosphorylation HPRD 18083107
S780 Phosphorylation HPRD 20068231
T788 Phosphorylation HPRD 17322306, 18767875
T1052 Phosphorylation HPRD 15302935


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K49 Q49 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T51 I51 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K56 E56 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K57 Q57 Biomuta DOID:1612 / breast cancer [ cosmic ]
T169 A169 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K370 T370 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T421 M421 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S422 P422 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T434 M434 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S435 P435 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T518 I518 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T706 I706 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y985 C985 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y985 D985 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1019 T1019 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1019 G1019 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1212 T1212 Biomuta DOID:363 / uterine cancer [ icgc ]
K1216 R1216 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S1353 R1353 Biomuta DOID:1324 / lung cancer [ cosmic ]