iPTMnet Report for Q9BZF1 (OSBPL8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZF1 / OSBL8_HUMAN
Protein Name Oxysterol-binding protein-related protein 8
Gene Name Name: OSBPL8
Synonyms:KIAA1451;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZF1
DAG View
PRO Name oxysterol-binding protein-related protein 8 (human)
Definition An oxysterol-binding protein-related protein 8 that is encoded in the genome of human.
Short Label hOSBPL8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZF1 (OSBPL8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T13 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
S32 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
T54 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S63 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S65 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S68 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 20068231, ...18220336
S71 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S82 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
K183 Acetylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K224 Acetylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S314 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S328 Phosphorylation PhosphoSitePlus   UniProt 21406692
S331 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus   UniProt 21406692
S350 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
K624 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
K664 Ubiquitination PhosphoSitePlus
K685 Ubiquitination PhosphoSitePlus
K697 Ubiquitination PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
K762 Ubiquitination PhosphoSitePlus
K769 Ubiquitination PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus
Y797 Phosphorylation PhosphoSitePlus
S798 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S799 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S807 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 24275569
S808 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 24275569
S810 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S814 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K816 Ubiquitination PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
K823 Ubiquitination PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
T840 Phosphorylation PhosphoSitePlus
Y864 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y52 Phosphorylation HPRD 17924679
T56 Phosphorylation HPRD 17924679
S63 Phosphorylation HPRD 19651622, 18669648, 20068231
S65 Phosphorylation HPRD 19651622, 18669648, 20068231
S68 Phosphorylation HPRD 19651622, 18669648, 20068231
S314 Phosphorylation HPRD 18669648, 20068231
Y327 Phosphorylation HPRD 19651622
S328 Phosphorylation HPRD 19651622
S331 Phosphorylation HPRD 19651622
S342 Phosphorylation HPRD 19651622
S350 Phosphorylation HPRD 19651622
S353 Phosphorylation HPRD 19651622
T355 Phosphorylation HPRD 19651622
T357 Phosphorylation HPRD 19651622
S358 Phosphorylation HPRD 19651622
T774 Phosphorylation HPRD 19413330
S798 Phosphorylation HPRD 19651622
S807 Phosphorylation HPRD 19651622, 18669648
S808 Phosphorylation HPRD 19651622, 18669648
S810 Phosphorylation HPRD 19651622, 18669648
S814 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
Y10 Phosphorylation HPRD 17924679
T14 Phosphorylation HPRD 17924679
S21 Phosphorylation HPRD 19651622, 18669648, 20068231
S23 Phosphorylation HPRD 19651622, 18669648, 20068231
S26 Phosphorylation HPRD 19651622, 18669648, 20068231
S272 Phosphorylation HPRD 18669648, 20068231
Y285 Phosphorylation HPRD 19651622
S286 Phosphorylation HPRD 19651622
S289 Phosphorylation HPRD 19651622
S300 Phosphorylation HPRD 19651622
S308 Phosphorylation HPRD 19651622
S311 Phosphorylation HPRD 19651622
T313 Phosphorylation HPRD 19651622
T315 Phosphorylation HPRD 19651622
S316 Phosphorylation HPRD 19651622
T732 Phosphorylation HPRD 19413330
S756 Phosphorylation HPRD 19651622
S765 Phosphorylation HPRD 19651622, 18669648
S766 Phosphorylation HPRD 19651622, 18669648
S768 Phosphorylation HPRD 19651622, 18669648
S772 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y10 S10 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S14 L14 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S14 * Biomuta DOID:1319 / brain cancer [ cosmic ]
S32 T32 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S35 F35 Biomuta DOID:363 / uterine cancer [ icgc ]
T39 K39 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y52 S52 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T54 M54 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]
S82 Y82 Biomuta DOID:363 / uterine cancer [ icgc, tcga ]
S97 F97 Biomuta DOID:4159 / skin cancer [ cosmic ]
K118 N118 Biomuta DOID:1324 / lung cancer [ cosmic ]
S120 Y120 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S284 I284 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y295 C295 Biomuta DOID:3571 / liver cancer [ cosmic ]
S305 N305 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S308 G308 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S308 R308 Biomuta [ cosmic ]
S316 T316 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S350 R350 Biomuta [ cosmic ]
S350 G350 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S358 T358 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K609 T609 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T732 N732 Biomuta DOID:363 / uterine cancer [ icgc ]
S756 F756 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S766 Y766 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T774 N774 Biomuta DOID:363 / uterine cancer [ icgc ]
S798 F798 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S808 Y808 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T819 A819 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]