Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZE4 / NOG1_HUMAN
Protein Name Nucleolar GTP-binding protein 1
Gene Name Name: GTPBP4
Synonyms:CRFG,NOG1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZE4
DAG View
PRO Name nucleolar GTP-binding protein 1 (human)
Definition A nucleolar GTP-binding protein 1 that is encoded in the genome of human.
Short Label hGTPBP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZE4 (GTPBP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Acetylation PhosphoSitePlus
K8 Sumoylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
R61 Methylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus   UniProt 19608861
K103 Ubiquitination PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus   UniProt 23186163
K127 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K181 Sumoylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K213 Acetylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
R233 Methylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K305 Sumoylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K332 Sumoylation PhosphoSitePlus
R338 Methylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K352 Sumoylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
Y409 Phosphorylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K449 Sumoylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
T461 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y466 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S468 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...19690332, 20068231
S470 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...19690332, 20068231
S472 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231, ...19690332
K494 Sumoylation PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
K513 Methylation PhosphoSitePlus
K522 Acetylation PhosphoSitePlus   UniProt 19608861
K522 Ubiquitination PhosphoSitePlus
K534 Sumoylation PhosphoSitePlus
Y539 Phosphorylation PhosphoSitePlus
S558 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S562 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S578 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
R581 Methylation PhosphoSitePlus
K584 Sumoylation PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
K625 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T461 Phosphorylation HPRD 18669648
Y466 Phosphorylation HPRD 18669648, 17081983
S468 Phosphorylation HPRD 19651622, 18691976, 18669648, ...17081983, 20068231
S470 Phosphorylation HPRD 18691976, 17081983, 19651622, ...18669648, 19415658, 20068231
S472 Phosphorylation HPRD 18691976, 17081983, 19651622, ...18669648, 19415658, 20068231
S558 Phosphorylation HPRD 18669648
S563 Phosphorylation HPRD 19007248
S578 Phosphorylation HPRD 18669648, 19007248, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K29 N29 Biomuta DOID:1612 / breast cancer [ tcga ]
K103 N103 Biomuta DOID:363 / uterine cancer [ tcga ]
T168 I168 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K181 N181 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K282 N282 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K347 R347 Biomuta DOID:1324 / lung cancer [ cosmic ]
S558 F558 Biomuta DOID:1909 / melanoma [ tcga ]
S578 F578 Biomuta DOID:0060119 / pharynx cancer [ cosmic ]
K625 N625 Biomuta DOID:3571 / liver cancer [ tcga ]