iPTMnet Report for Q9BZC7 (ABCA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZC7 / ABCA2_HUMAN
Protein Name ATP-binding cassette sub-family A member 2
Gene Name Name: ABCA2
Synonyms:ABC2,KIAA1062;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZC7
DAG View
PRO Name ATP-binding cassette sub-family A member 2 (human)
Definition An ATP-binding cassette sub-family A member 2 that is encoded in the genome of human.
Short Label hABCA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZC7 (ABCA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S137 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
Q271 Methylation UniProt 26797129
S280 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
N628 N-Glycosylation GlyGen 29741879
T635 Phosphorylation IEDB 35494241
S958 Phosphorylation PhosphoSitePlus
S1045 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
T1049 Phosphorylation PhosphoSitePlus
Y1051 Phosphorylation PhosphoSitePlus
T1057 Phosphorylation PhosphoSitePlus
S1093 Phosphorylation PhosphoSitePlus
K1105 Ubiquitination PhosphoSitePlus
S1118 Phosphorylation PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus
K1128 Methylation PhosphoSitePlus
S1132 Phosphorylation PhosphoSitePlus
S1141 O-Glycosylation GlyGen 28510447, 29237092
K1167 Acetylation PhosphoSitePlus
Y1216 Phosphorylation PhosphoSitePlus
T1219 Phosphorylation PhosphoSitePlus
K1222 Ubiquitination PhosphoSitePlus
S1238 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1327 Phosphorylation PhosphoSitePlus   UniProt 17081983
S1331 Phosphorylation PhosphoSitePlus   UniProt 17081983, 24275569
K1336 Ubiquitination PhosphoSitePlus
S1338 Phosphorylation PhosphoSitePlus
K1340 Ubiquitination PhosphoSitePlus
S1351 Phosphorylation PhosphoSitePlus
Y1393 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
S1530 Phosphorylation PhosphoSitePlus
T1531 Phosphorylation PhosphoSitePlus
N1549 N-Glycosylation GlyGen 24190977
N1557 N-Glycosylation GlyGen 24190977
S1563 Phosphorylation PhosphoSitePlus
N1587 N-Glycosylation GlyGen 24190977
Y1694 Phosphorylation PhosphoSitePlus
K1704 Ubiquitination PhosphoSitePlus
S1705 Phosphorylation PhosphoSitePlus
T1712 Phosphorylation PhosphoSitePlus
Y1731 Phosphorylation PhosphoSitePlus
K2025 Ubiquitination PhosphoSitePlus
T2056 Phosphorylation PhosphoSitePlus
T2101 Phosphorylation PhosphoSitePlus
S2117 Phosphorylation PhosphoSitePlus
Y2178 Phosphorylation PhosphoSitePlus
Y2186 Phosphorylation PhosphoSitePlus
S2322 Phosphorylation PhosphoSitePlus
S2326 Phosphorylation PhosphoSitePlus
S2332 Phosphorylation PhosphoSitePlus
S2381 Phosphorylation PhosphoSitePlus
T2412 Phosphorylation PhosphoSitePlus   UniProt 18669648
S2419 Phosphorylation PhosphoSitePlus
S2428 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
Y57 Phosphorylation PhosphoSitePlus
T58 Phosphorylation PhosphoSitePlus
T252 Phosphorylation HPRD 20068231
S1328 Phosphorylation HPRD 19651622, 17081983
S1332 Phosphorylation HPRD 19651622, 17081983
T2413 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T282 Phosphorylation HPRD 20068231
S1358 Phosphorylation HPRD 19651622, 17081983
S1362 Phosphorylation HPRD 19651622, 17081983
T2443 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T251 A251 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T252 A252 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Q271 L271 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Q271 H271 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S283 F283 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S1045 L1045 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T1057 M1057 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1105 N1105 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1132 F1132 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1238 I1238 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1331 N1331 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1332 N1332 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1410 N1410 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1531 M1531 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1705 F1705 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S2322 L2322 Biomuta DOID:263 / kidney cancer [ cosmic ]