iPTMnet Report for Q9BZ67 (FRMD8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZ67 / FRMD8_HUMAN
Protein Name FERM domain-containing protein 8
Gene Name Name: FRMD8
ORFNames:FKSG44;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZ67
DAG View
PRO Name FERM domain-containing protein 8 (human)
Definition A FERM domain-containing protein 8 that is encoded in the genome of human.
Short Label hFRMD8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZ67 (FRMD8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S17 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
C176 Methylation IEDB 31844290
K196 Ubiquitination PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
R217 Methylation PhosphoSitePlus
R219 Methylation PhosphoSitePlus
R222 Methylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
C269 Methylation IEDB 31844290
K309 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus   UniProt 24275569
S387 Phosphorylation PhosphoSitePlus   UniProt 24275569
S392 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus   UniProt 24275569
S418 Phosphorylation PhosphoSitePlus
T419 Phosphorylation PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
T437 Phosphorylation PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
S439 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S446 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S460 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T437 Phosphorylation HPRD 20068231
S439 Phosphorylation HPRD 18669648, 20068231
S446 Phosphorylation HPRD 19664995, 20068231
T453 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 I20 Biomuta DOID:3571 / liver cancer [ cosmic ]
R217 W217 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K352 E352 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K352 N352 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S387 L387 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S392 R392 Biomuta DOID:1612 / breast cancer [ icgc ]
K427 E427 Biomuta DOID:1324 / lung cancer [ cosmic ]
T453 I453 Biomuta DOID:1612 / breast cancer [ cosmic ]