iPTMnet Report for Q9BZ23 (PANK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BZ23 / PANK2_HUMAN
Protein Name Pantothenate kinase 2, mitochondrial precursor
Gene Name Name: PANK2
Synonyms:C20orf48;
Organism Homo sapiens (Human)

PRO ID PR:Q9BZ23
DAG View
PRO Name pantothenate kinase 2, mitochondrial (human)
Definition A pantothenate kinase 2, mitochondrial that is encoded in the genome of human.
Short Label hPANK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BZ23 (PANK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S140 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S168 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18669648, 24275569, 19690332
S169 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S171 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T182 O-Glycosylation GlyGen 30379171, 29351928
S189 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18669648, 24275569, 19690332, 20068231
Y190 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
Y400 Phosphorylation PhosphoSitePlus
Y405 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S168 Phosphorylation HPRD 19413330, 20166139, 18669648
S169 Phosphorylation HPRD 18669648
S171 Phosphorylation HPRD 18669648
S189 Phosphorylation HPRD 19413330, 18691976, 18212344, ...20058876, 19664994, 19664995, 19651622, 17322306, 18669648, 18767875, 20166139, 20068231
Y190 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S189 C189 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S191 R191 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y405 C405 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]