iPTMnet Report for Q9BYX2 (TBC1D2)
Protein Information
| UniProt AC / UniProt ID | Q9BYX2 / TBD2A_HUMAN |
| Protein Name | TBC1 domain family member 2A |
| Gene Name | Name: TBC1D2 Synonyms:PARIS1,PP8997,TBC1D2A; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BYX2 |
| PRO Name | TBC1 domain family member 2A (human) |
| Definition | A TBC1 domain family member 2A that is encoded in the genome of human. |
| Short Label | hTBC1D2 |
| Category | organism-gene |
Q9BYX2 (TBC1D2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S66 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T115 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T186 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
| S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K209 | Methylation | score1 | PhosphoSitePlus | |||
| S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S267 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K283 | Methylation | score1 | PhosphoSitePlus | |||
| K285 | Methylation | score1 | PhosphoSitePlus | |||
| T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K334 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K343 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K410 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S436 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 18220336 | ||
| K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K458 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K495 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y571 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K577 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K581 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K619 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T789 | Phosphorylation | score1 | IEDB | 35494241 | ||
| Y846 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S857 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S859 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K900 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S909 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 15302935, 17081983 | ||
| S915 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 17081983 | ||
| S920 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 17081983 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K283 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T789 | I789 | Biomuta | [ cosmic ] |
DAG View