iPTMnet Report for Q9BYV9 (BACH2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BYV9 / BACH2_HUMAN
Protein Name Transcription regulator protein BACH2
Gene Name Name: BACH2
Organism Homo sapiens (Human)

PRO ID PR:Q9BYV9
DAG View
PRO Name transcription regulator protein BACH2 (human)
Definition A transcription regulator protein BACH2 that is encoded in the genome of human.
Short Label hBACH2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BYV9 (BACH2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S159 Phosphorylation PhosphoSitePlus
K202 Sumoylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K276 Sumoylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
T383 O-Glycosylation GlyGen 29351928
T386 O-Glycosylation GlyGen 29351928
T389 O-Glycosylation GlyGen 29351928
K400 Ubiquitination PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
K421 Sumoylation PhosphoSitePlus
T443 O-Glycosylation GlyGen 29351928
S444 O-Glycosylation GlyGen 29351928
S459 O-Glycosylation GlyGen 29351928
S476 O-Glycosylation GlyGen 29351928
S499 O-Glycosylation GlyGen 29351928
S510 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus   RLIMS-P 27158840
S521 Phosphorylation P23443 (RPS6KB1) PhosphoSitePlus   RLIMS-P   UniProt 17018862
S525 Phosphorylation PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
Y572 Phosphorylation PhosphoSitePlus
K580 Sumoylation PhosphoSitePlus
T832 O-Glycosylation GlyGen 29351928


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S159 F159 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K267 T267 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S315 I315 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T319 A319 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T319 P319 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S337 L337 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K400 N400 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]
S409 L409 Biomuta DOID:4159 / skin cancer [ cosmic ]
T443 S443 Biomuta DOID:2021 / placenta cancer [ cosmic ]
S459 P459 Biomuta DOID:3571 / liver cancer [ cosmic ]
S525 T525 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S525 F525 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T832 A832 Biomuta DOID:2531 / hematologic cancer [ cosmic ]