iPTMnet Report for Q9BYM8 (RBCK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BYM8 / HOIL1_HUMAN
Protein Name RanBP-type and C3HC4-type zinc finger-containing protein 1
Gene Name Name: RBCK1
Synonyms:C20orf18,RNF54,UBCE7IP3,XAP3;
Organism Homo sapiens (Human)

PRO ID PR:Q9BYM8
DAG View
PRO Name RanBP-type and C3HC4-type zinc finger-containing protein 1 (human)
Definition A RanBP-type and C3HC4-type zinc finger-containing protein 1 that is encoded in the genome of human.
Short Label hRBCK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BYM8 (RBCK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K29 Ubiquitination PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus   UniProt 23186163
S132 Ubiquitination PhosphoSitePlus
T136 Ubiquitination PhosphoSitePlus
S137 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus   UniProt 15951569
S331 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
K335 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y330 Phosphorylation HPRD 15951569
Site PTM Type PTM Enzyme Score Source PMID
Y288 Phosphorylation HPRD 15951569


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K29 R29 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S331 L331 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S333 L333 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K335 N335 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K335 R335 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T346 I346 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S368 R368 Biomuta DOID:9256 / colorectal cancer [ cosmic ]