iPTMnet Report for Q9BYJ4 (TRIM34)
Protein Information
UniProt AC / UniProt ID | Q9BYJ4 / TRI34_HUMAN |
Protein Name | E3 ubiquitin-protein ligase TRIM34 |
Gene Name | Name: TRIM34 Synonyms:IFP1,RNF21; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BYJ4 |
PRO Name | E3 ubiquitin-protein ligase TRIM34 (human) |
Definition | An E3 ubiquitin-protein ligase TRIM34 that is encoded in the genome of human. |
Short Label | hTRIM34 |
Category | organism-gene |
Q9BYJ4 (TRIM34) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
K85 | Acetylation | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K93 | Acetylation | score1 | PhosphoSitePlus | |||
K93 | Methylation | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
C140 | Methylation | score1 | IEDB | 31844290 | ||
K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
T185 | Phosphorylation | score1 | PhosphoSitePlus | |||
K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
C239 | Methylation | score1 | IEDB | 31844290 | ||
K273 | Acetylation | score1 | PhosphoSitePlus | |||
K275 | Acetylation | score1 | PhosphoSitePlus | |||
S317 | Phosphorylation | score1 | IEDB | 35494241 | ||
K357 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K173 | N173 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
T185 | A185 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K215 | E215 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S317 | L317 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K357 | M357 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K357 | N357 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |