Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BYI3 / HYCCI_HUMAN
Protein Name Hyccin
Gene Name Name: FAM126A
Synonyms:DRCTNNB1A;
Organism Homo sapiens (Human)

PRO ID PR:Q9BYI3
DAG View
PRO Name hyccin (human)
Definition A hyccin that is encoded in the genome of human.
Short Label hFAM126A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BYI3 (FAM126A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation PhosphoSitePlus
S4 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
T18 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K292 Methylation PhosphoSitePlus
C300 S-Nitrosylation dbSNO 26338901
T306 Phosphorylation PhosphoSitePlus   UniProt 23186163
S313 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
R323 Methylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus   UniProt 23186163
S422 Phosphorylation PhosphoSitePlus   UniProt 23186163
K424 Methylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus   UniProt 23186163
K452 Ubiquitination PhosphoSitePlus
S453 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S485 Phosphorylation PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
Y493 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T306 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 L4 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S208 L208 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
C300 R300 Biomuta DOID:363 / uterine cancer [ tcga ]
C300 Y300 Biomuta DOID:1324 / lung cancer [ tcga ]
T306 A306 Biomuta DOID:9256 / colorectal cancer [ tcga ]
R323 T323 Biomuta DOID:3571 / liver cancer [ icgc ]