iPTMnet Report for Q9BYG8 (GSDMC)
Protein Information
| UniProt AC / UniProt ID | Q9BYG8 / GSDMC_HUMAN |
| Protein Name | Gasdermin-C |
| Gene Name | Name: GSDMC Synonyms:MLZE; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BYG8 |
| PRO Name | gasdermin-C (human) |
| Definition | A gasdermin-C that is encoded in the genome of human. |
| Short Label | hGSDMC |
| Category | organism-gene |
Q9BYG8 (GSDMC) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S84 | Phosphorylation | score1 | IEDB | 35494241 | ||
| Y343 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S344 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S3 | C3 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S3 | F3 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S84 | G84 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S344 | N344 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S344 | I344 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View