iPTMnet Report for Q9BYE7 (PCGF6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BYE7 / PCGF6_HUMAN
Protein Name Polycomb group RING finger protein 6
Gene Name Name: PCGF6
Synonyms:MBLR,RNF134;
Organism Homo sapiens (Human)

PRO ID PR:Q9BYE7
DAG View
PRO Name Polycomb group RING finger protein 6 (human)
Definition A Polycomb group RING finger protein 6 that is encoded in the genome of human.
Short Label hPCGF6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BYE7 (PCGF6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation PhosphoSitePlus
S30 Phosphorylation P50613 (CDK7) neXtProt   PhosphoSitePlus   UniProt 12167161
S102 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 20068231, ...24275569
Y164 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation P50613 (CDK7) HPRD 12167161
S115 Phosphorylation HPRD 19651622, 20068231
S280 Phosphorylation HPRD 20068231
T284 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation P50613 (CDK7) HPRD 12167161
S115 Phosphorylation HPRD 19651622, 20068231
S205 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S105 L105 Biomuta DOID:4159 / skin cancer [ cosmic ]
S115 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S115 A115 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y164 C164 Biomuta DOID:1324 / lung cancer [ cosmic ]
S205 L205 Biomuta DOID:4159 / skin cancer [ cosmic ]
S280 L280 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc, cosmic ]