iPTMnet Report for Q9BYE2 (TMPRSS13)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BYE2 / TMPSD_HUMAN
Protein Name Transmembrane protease serine 13
Gene Name Name: TMPRSS13
Synonyms:MSP,TMPRSS11;
Organism Homo sapiens (Human)

PRO ID PR:Q9BYE2
DAG View
PRO Name transmembrane protease serine 13 (human)
Definition A transmembrane protease serine 13 that is encoded in the genome of human.
Short Label hTMPRSS13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BYE2 (TMPRSS13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
Y120 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
T152 O-Glycosylation GlyGen 34019948, 30620550
S298 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
N405 N-Glycosylation UniProt 34562451
N445 N-Glycosylation UniProt 34562451
T459 Phosphorylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 N5 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T64 I64 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S70 P70 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S111 L111 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y120 H120 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]