Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BY77 / PDIP3_HUMAN
Protein Name Polymerase delta-interacting protein 3
Gene Name Name: POLDIP3
Synonyms:KIAA1649,PDIP46;
Organism Homo sapiens (Human)

PRO ID PR:Q9BY77
DAG View
PRO Name polymerase delta-interacting protein 3 (human)
Definition A polymerase delta-interacting protein 3 that is encoded in the genome of human.
Short Label hPOLDIP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BY77 (POLDIP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895, 20068231
S5 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
R11 Methylation PhosphoSitePlus
R33 Methylation PhosphoSitePlus   UniProt 24129315
S42 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S44 Phosphorylation PhosphoSitePlus   UniProt 23186163
S63 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
R66 Methylation PhosphoSitePlus
K88 Methylation PhosphoSitePlus
K102 Methylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S126 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S127 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...15341740
T140 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
K144 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus   UniProt 23186163
S215 Phosphorylation PhosphoSitePlus   UniProt 23186163
S217 Phosphorylation PhosphoSitePlus   UniProt 23186163
K223 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus   UniProt 23186163
K248 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
S275 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 20068231, 15341740
C301 S-Nitrosylation dbSNO 26338901
C303 S-Nitrosylation dbSNO 26338901
K307 Acetylation PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
S383 Phosphorylation P23443 (RPS6KB1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15341740
S385 Phosphorylation P23443 (RPS6KB1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15341740
S387 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K404 Methylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
S406 Phosphorylation phospho.ELM   PhosphoSitePlus 15341740
S409 Phosphorylation PhosphoSitePlus
K418 Methylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 20068231
S42 Phosphorylation HPRD 17525332
S63 Phosphorylation HPRD 20068231
T105 Phosphorylation HPRD 20068231
T106 Phosphorylation HPRD 20068231
S126 Phosphorylation HPRD 18669648, 20068231
S127 Phosphorylation HPRD 18669648, 20068231, 17924679
T140 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 20068231
S42 Phosphorylation HPRD 17525332
S63 Phosphorylation HPRD 20068231
T105 Phosphorylation HPRD 20068231
T106 Phosphorylation HPRD 20068231
S126 Phosphorylation HPRD 18669648, 20068231
S127 Phosphorylation HPRD 18669648, 20068231, 17924679
T140 Phosphorylation HPRD 18669648, 20068231
K147 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
S246 Phosphorylation HPRD 20068231
S339 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R11 T11 Biomuta DOID:1612 / breast cancer [ tcga ]
R33 * Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T237 K237 Biomuta DOID:3571 / liver cancer [ icgc ]
K265 E265 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
C303 Y303 Biomuta DOID:9256 / colorectal cancer [ tcga ]
C303 W303 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S383 Y383 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S405 C405 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]