iPTMnet Report for Q9BY42 (RTF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BY42 / RTF2_HUMAN
Protein Name Replication termination factor 2
Gene Name Name: RTF2
Synonyms:C20orf43,RTFDC1;ORFNames:AD-007,CDA05,HSPC164,HSPC169;
Organism Homo sapiens (Human)

PRO ID PR:Q9BY42
DAG View
PRO Name replication termination factor 2 (human)
Definition A replication termination factor 2 that is encoded in the genome of human.
Short Label hRTF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BY42 (RTF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
C51 Methylation IEDB 31844290
K59 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
K77 Sumoylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K83 Sumoylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K86 Sumoylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K92 Sumoylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
C121 Methylation IEDB 31844290
K183 Sumoylation PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K210 Acetylation PhosphoSitePlus
K210 Sumoylation PhosphoSitePlus
K224 Sumoylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
K227 Sumoylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
K239 Sumoylation PhosphoSitePlus
K245 Sumoylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K266 Acetylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
S268 O-Glycosylation GlyGen 30379171, 34019948, 28510447, ...31373491
S268 Phosphorylation HPRD   PhosphoSitePlus 18212344
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
K279 Sumoylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
S280 O-Glycosylation GlyGen 30379171, 34019948, 28510447, ...31373491
T283 O-Glycosylation GlyGen 31373491
T283 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S287 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K289 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K10 N10 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K59 R59 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K69 T69 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S207 T207 Biomuta DOID:1612 / breast cancer [ cosmic ]
T283 I283 Biomuta DOID:4159 / skin cancer [ cosmic ]
K289 M289 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]