iPTMnet Report for Q9BY32 (ITPA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BY32 / ITPA_HUMAN
Protein Name Inosine triphosphate pyrophosphatase
Gene Name Name: ITPA
Synonyms:C20orf37;ORFNames:My049,OK/SW-cl.9;
Organism Homo sapiens (Human)

PRO ID PR:Q9BY32
DAG View
PRO Name inosine triphosphate pyrophosphatase (human)
Definition An inosine triphosphate pyrophosphatase that is encoded in the genome of human.
Short Label hITPA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BY32 (ITPA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K19 Acetylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
C146 S-Nitrosylation dbSNO 26338901
C154 S-Nitrosylation dbSNO 26338901
K169 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K9 R9 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K19 N19 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K39 E39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K39 N39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K56 N56 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S111 L111 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S111 P111 Biomuta DOID:9256 / colorectal cancer [ cosmic ]