iPTMnet Report for Q9BY11 (PACSIN1)
Protein Information
| UniProt AC / UniProt ID | Q9BY11 / PACN1_HUMAN |
| Protein Name | Protein kinase C and casein kinase substrate in neurons protein 1 |
| Gene Name | Name: PACSIN1 Synonyms:KIAA1379; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BY11 |
| PRO Name | protein kinase C and casein kinase substrate in neurons protein 1 (human) |
| Definition | A protein kinase C and casein kinase substrate in neurons protein 1 that is encoded in the genome of human. |
| Short Label | hPACSIN1 |
| Category | organism-gene |
Q9BY11 (PACSIN1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K65 | Acetylation | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S346 | Phosphorylation | Q9NQU5 (PAK6) | score4 | neXtProt PhosphoSitePlus | 24204982, 22371566 | |
| S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S430 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S182 | L182 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S365 | R365 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View