iPTMnet Report for Q9BY11 (PACSIN1)
Protein Information
UniProt AC / UniProt ID | Q9BY11 / PACN1_HUMAN |
Protein Name | Protein kinase C and casein kinase substrate in neurons protein 1 |
Gene Name | Name: PACSIN1 Synonyms:KIAA1379; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BY11 |
PRO Name | protein kinase C and casein kinase substrate in neurons protein 1 (human) |
Definition | A protein kinase C and casein kinase substrate in neurons protein 1 that is encoded in the genome of human. |
Short Label | hPACSIN1 |
Category | organism-gene |
Q9BY11 (PACSIN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K65 | Acetylation | score1 | PhosphoSitePlus | |||
S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
T184 | Phosphorylation | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | Q9NQU5 (PAK6) | score4 | neXtProt PhosphoSitePlus | 24204982, 22371566 | |
S348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S349 | Phosphorylation | score1 | PhosphoSitePlus | |||
S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
S430 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S182 | L182 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S365 | R365 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |