Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BY07 / S4A5_HUMAN
Protein Name Electrogenic sodium bicarbonate cotransporter 4
Gene Name Name: SLC4A5
Synonyms:NBC4;
Organism Homo sapiens (Human)

PRO ID PR:Q9BY07
DAG View
PRO Name electrogenic sodium bicarbonate cotransporter 4 (human)
Definition An electrogenic sodium bicarbonate cotransporter 4 that is encoded in the genome of human.
Short Label hSLC4A5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BY07 (SLC4A5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S52 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
Y662 Phosphorylation PhosphoSitePlus
Y663 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
K773 Ubiquitination PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S52 A52 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T173 M173 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:363 / uterine cancer [ tcga ]
S641 Y641 Biomuta DOID:3571 / liver cancer [ icgc ]
S641 C641 Biomuta DOID:1612 / breast cancer [ cosmic ]
S747 F747 Biomuta DOID:363 / uterine cancer [ tcga ]