iPTMnet Report for Q9BXW6 (OSBPL1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXW6 / OSBL1_HUMAN
Protein Name Oxysterol-binding protein-related protein 1
Gene Name Name: OSBPL1A
Synonyms:ORP1,OSBP8,OSBPL1,OSBPL1B;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXW6
DAG View
PRO Name oxysterol-binding protein-related protein 1 (human)
Definition An oxysterol-binding protein-related protein 1 that is encoded in the genome of human.
Short Label hOSBPL1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXW6 (OSBPL1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
Y238 Phosphorylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
K382 Methylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
K424 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S490 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T496 Phosphorylation PhosphoSitePlus
S499 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
S509 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
R637 Methylation PhosphoSitePlus
K682 Ubiquitination PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
K763 Ubiquitination PhosphoSitePlus
S764 O-Glycosylation GlyGen 30379171
K791 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S499 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S317 N317 Biomuta DOID:1324 / lung cancer [ cosmic ]
S465 T465 Biomuta DOID:263 / kidney cancer [ cosmic ]
R637 Q637 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R637 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]