iPTMnet Report for Q9BXS6 (NUSAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXS6 / NUSAP_HUMAN
Protein Name Nucleolar and spindle-associated protein 1
Gene Name Name: NUSAP1
Synonyms:ANKT;ORFNames:BM-037,PRO0310;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXS6
DAG View
PRO Name nucleolar and spindle-associated protein 1 (human)
Definition A nucleolar and spindle-associated protein 1 that is encoded in the genome of human.
Short Label hNUSAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXS6 (NUSAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
T33 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S124 Phosphorylation Q13315 (ATM) phospho.ELM   PhosphoSitePlus   UniProt 21130744, 17525332
S135 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...16565220
S148 Phosphorylation phospho.ELM 18669648
S149 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S154 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
T182 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K186 Methylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
S240 O-Glycosylation GlyGen 31373491
S240 Phosphorylation Q96GD4 (AURKB) , O14965 (AURKA) phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 18669648, ...22267324, 21072059, 20068231
S243 O-Glycosylation GlyGen 31373491
S243 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T244 O-Glycosylation GlyGen 31373491
T244 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S247 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S251 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus   UniProt 23186163
C256 Methylation IEDB 31844290
C256 S-Nitrosylation dbSNO 26338901
S260 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
K267 Methylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus   UniProt 23186163
K271 Methylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus   UniProt 20068231
K279 Ubiquitination PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
T300 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus   Signor 22101338
K304 Ubiquitination PhosphoSitePlus
S305 O-Glycosylation GlyGen 31373491
S305 Phosphorylation PhosphoSitePlus
S311 O-Glycosylation GlyGen 31373491
S311 Phosphorylation PhosphoSitePlus   UniProt 20068231
T314 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K316 Ubiquitination PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
T338 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 18669648, 23186163, 19690332, ...22101338
T343 Phosphorylation PhosphoSitePlus
T344 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T347 Phosphorylation PhosphoSitePlus
T349 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S352 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K355 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus   UniProt 23186163
S365 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K384 Methylation PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K411 Acetylation PhosphoSitePlus   UniProt 19608861
Site PTM Type PTM Enzyme Score Source PMID
S62 Phosphorylation HPRD 18452278
S63 Phosphorylation HPRD 18452278
S101 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD 19691289, 18452278, 19651622, ...18669648, 19007248, 20068231
S148 Phosphorylation HPRD 18669648
S149 Phosphorylation HPRD 18669648
T182 Phosphorylation HPRD 18669648, 20068231
S215 Phosphorylation HPRD 20068231
S240 Phosphorylation HPRD 18077418, 20068230, 18669648, ...20068231, 18212344
S243 Phosphorylation HPRD 18669648
T244 Phosphorylation HPRD 18077418, 18669648, 18212344
S247 Phosphorylation HPRD 18077418, 18669648, 20068231
S255 Phosphorylation HPRD 20068231
S276 Phosphorylation HPRD 20068231
S305 Phosphorylation HPRD 20068231
T309 Phosphorylation HPRD 20068231
S311 Phosphorylation HPRD 20068231
T314 Phosphorylation HPRD 18669648, 20068231, 17924679
T338 Phosphorylation HPRD 18669648
T344 Phosphorylation HPRD 18669648
T349 Phosphorylation HPRD 19413330, 18669648
S352 Phosphorylation HPRD 19413330, 18669648, 20068231
S363 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S62 Phosphorylation HPRD 18452278
S63 Phosphorylation HPRD 18452278
S101 Phosphorylation HPRD 20068231
S124 Phosphorylation HPRD 17525332
S135 Phosphorylation HPRD 19007248, 16565220, 19651622, ...18669648, 18452278, 20068231, 19691289
S148 Phosphorylation HPRD 18669648
S149 Phosphorylation HPRD 18669648
T182 Phosphorylation HPRD 18669648, 20068231
S215 Phosphorylation HPRD 20068231
S239 Phosphorylation HPRD 18077418, 20068230, 18669648, ...20068231, 18212344
S242 Phosphorylation HPRD 18669648
T243 Phosphorylation HPRD 18077418, 18669648, 18212344
S246 Phosphorylation HPRD 18077418, 18669648, 20068231
S254 Phosphorylation HPRD 20068231
S275 Phosphorylation HPRD 20068231
S304 Phosphorylation HPRD 20068231
T308 Phosphorylation HPRD 20068231
S310 Phosphorylation HPRD 20068231
T313 Phosphorylation HPRD 18669648, 20068231, 17924679
T337 Phosphorylation HPRD 18669648
T343 Phosphorylation HPRD 18669648
T348 Phosphorylation HPRD 19413330, 18669648
S351 Phosphorylation HPRD 19413330, 18669648, 20068231
S362 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S149 L149 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S242 Y242 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S254 Y254 Biomuta DOID:4159 / skin cancer [ cosmic ]
S275 F275 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S275 C275 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S304 T304 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T348 A348 Biomuta DOID:5158 / pleural cancer [ cosmic ]