Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXP8 / PAPP2_HUMAN
Protein Name Pappalysin-2 precursor
Gene Name Name: PAPPA2
Synonyms:PLAC3;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXP8
DAG View
PRO Name pappalysin-2 (human)
Definition A pappalysin-2 that is encoded in the genome of human.
Short Label hPAPPA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXP8 (PAPPA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
Y666 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
Y806 Phosphorylation PhosphoSitePlus
Y829 Phosphorylation PhosphoSitePlus
Y834 Phosphorylation PhosphoSitePlus
Y908 Phosphorylation PhosphoSitePlus
T910 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 I10 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S21 F21 Biomuta DOID:11934 / head and neck cancer [ tcga ]
T29 K29 Biomuta DOID:1324 / lung cancer [ tcga ]
S357 G357 Biomuta DOID:5041 / esophageal cancer [ icgc ]
Y806 C806 Biomuta DOID:1324 / lung cancer [ tcga ]