iPTMnet Report for Q9BXP8 (PAPPA2)
Protein Information
| UniProt AC / UniProt ID | Q9BXP8 / PAPP2_HUMAN |
| Protein Name | Pappalysin-2 precursor |
| Gene Name | Name: PAPPA2 Synonyms:PLAC3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BXP8 |
| PRO Name | pappalysin-2 (human) |
| Definition | A pappalysin-2 that is encoded in the genome of human. |
| Short Label | hPAPPA2 |
| Category | organism-gene |
DAG ViewQ9BXP8 (PAPPA2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y666 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T804 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y806 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y829 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y834 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y908 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T910 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1103 | Phosphorylation | score1 | IEDB | 35494241 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S10 | I10 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S21 | F21 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| T29 | K29 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S234 | G234 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S357 | G357 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S1103 | L1103 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] |
