iPTMnet Report for Q9BXP5 (SRRT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXP5 / SRRT_HUMAN
Protein Name Serrate RNA effector molecule homolog
Gene Name Name: SRRT
Synonyms:ARS2,ASR2;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXP5
DAG View
PRO Name serrate RNA effector molecule homolog (human)
Definition A serrate RNA effector molecule that is encoded in the genome of human.
Short Label hSRRT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXP5 (SRRT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Acetylation UniProt 21406692, 20068231
S4 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
Y8 Phosphorylation PhosphoSitePlus   UniProt 17081983
S21 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
R41 Methylation PhosphoSitePlus
R45 Methylation PhosphoSitePlus
R47 Methylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
R52 Methylation PhosphoSitePlus
Y55 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S74 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
Y92 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
S136 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K150 Sumoylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
K200 Acetylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
K346 Acetylation PhosphoSitePlus
K347 Acetylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
K413 Sumoylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
R471 Methylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
C479 Methylation IEDB 31844290
S493 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18220336, ...18669648, 20068231
K514 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
K526 Acetylation PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
R534 Methylation PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
S540 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
T544 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 17693683, 19690332, 20068231, 17924679
T549 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus   UniProt 24275569
S580 Phosphorylation PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
Y615 Phosphorylation PhosphoSitePlus
Y624 Phosphorylation PhosphoSitePlus
Y625 Phosphorylation PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus
C640 S-Nitrosylation dbSNO 19483679
K669 Sumoylation PhosphoSitePlus
K669 Ubiquitination PhosphoSitePlus
T671 Phosphorylation PhosphoSitePlus   UniProt 23186163
S675 Phosphorylation PhosphoSitePlus
S679 O-Glycosylation GlyGen 34846842, 33214551, 34725712, ...34019948, 28510447
S679 Phosphorylation PhosphoSitePlus   UniProt 23186163
K687 Ubiquitination PhosphoSitePlus
K710 Acetylation PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
K712 Acetylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
K720 Acetylation PhosphoSitePlus
K739 Acetylation PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
K758 Acetylation PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus
T782 Phosphorylation PhosphoSitePlus
Y787 Phosphorylation PhosphoSitePlus
T791 Phosphorylation PhosphoSitePlus
Y798 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
R814 Methylation PhosphoSitePlus
R833 Methylation PhosphoSitePlus   UniProt 24129315
Y836 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
R840 Methylation PhosphoSitePlus   UniProt 24129315
R850 Methylation PhosphoSitePlus   UniProt 24129315
R855 Methylation PhosphoSitePlus
R859 Methylation PhosphoSitePlus
Y864 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 19413330, 19651622, 20068231
S67 Phosphorylation HPRD 17322306, 19651622, 20068231
S74 Phosphorylation HPRD 17322306, 18212344, 19664995, ...18452278, 19651622, 18707149, 20166139, 20068231
S136 Phosphorylation HPRD 18669648
S357 Phosphorylation HPRD 18452278
S366 Phosphorylation HPRD 18452278
S372 Phosphorylation HPRD 18452278
S374 Phosphorylation HPRD 18452278
S376 Phosphorylation HPRD 18452278
S493 Phosphorylation HPRD 17081983, 18767875, 18452278, ...18669648, 19415658, 20068231
T530 Phosphorylation HPRD 20068231
S540 Phosphorylation HPRD 18669648, 16964243, 20068231
T544 Phosphorylation HPRD 19413330, 15302935, 19664995, ...18452278, 19651622, 18669648, 17693683, 15345747, 19415658, 20068231, 17924679
S570 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S357 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R41 I41 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R45 S45 Biomuta DOID:263 / kidney cancer [ cosmic ]
R45 H45 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R45 C45 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ]
R47 H47 Biomuta [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S74 T74 Biomuta DOID:1319 / brain cancer [ cosmic ]
S136 I136 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y172 C172 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S357 G357 Biomuta DOID:1319 / brain cancer [ cosmic ]
S372 L372 Biomuta DOID:263 / kidney cancer [ cosmic ]
S374 * Biomuta DOID:1612 / breast cancer [ cosmic ]
T530 M530 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S540 L540 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T544 M544 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T549 K549 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S553 L553 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K604 N604 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y630 C630 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K720 R720 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K745 R745 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R814 H814 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y836 C836 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R850 C850 Biomuta DOID:1324 / lung cancer [ cosmic ]
R850 H850 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y864 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]