iPTMnet Report for Q9BXL7 (CARD11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXL7 / CAR11_HUMAN
Protein Name Caspase recruitment domain-containing protein 11
Gene Name Name: CARD11
Synonyms:CARMA1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXL7
DAG View
PRO Name caspase recruitment domain-containing protein 11 (human)
Definition A caspase recruitment domain-containing protein 11 that is encoded in the genome of human.
Short Label hCARD11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXL7 (CARD11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y11 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
S116 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus 16809782
T117 Phosphorylation PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
S285 O-Glycosylation GlyGen 30379171, 31492838
S433 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus   UniProt 23186163
S459 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus   UniProt 19690332
S487 Phosphorylation PhosphoSitePlus
Y489 Phosphorylation PhosphoSitePlus
Y493 Phosphorylation PhosphoSitePlus
S512 Phosphorylation IEDB   PhosphoSitePlus   UniProt 23186163, 29493099, 27869121, ...31848261
S515 Phosphorylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus   UniProt 23186163
S538 Phosphorylation PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
T549 Phosphorylation PhosphoSitePlus
S556 Phosphorylation Q92918 (MAP4K1) PhosphoSitePlus 19706536
S558 Phosphorylation Q92918 (MAP4K1) PhosphoSitePlus 19706536
S559 Phosphorylation Q04759 (PRKCQ) , P05771 (PRKCB) neXtProt   PRO   PhosphoSitePlus 16356855, 16356856
S562 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S615 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19118383
S644 Phosphorylation P05771 (PRKCB) , Q04759 (PRKCQ) neXtProt   PRO   PhosphoSitePlus   Signor 21157432, 16356855
S652 Phosphorylation P05771 (PRKCB) , Q04759 (PRKCQ) neXtProt   PRO   PhosphoSitePlus 16356855
T654 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
K696 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
Y751 Phosphorylation PhosphoSitePlus
S854 Phosphorylation PhosphoSitePlus
T861 Phosphorylation PhosphoSitePlus
T864 Phosphorylation PhosphoSitePlus
T871 O-Glycosylation GlyGen 30379171, 31492838
T871 Phosphorylation PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus   UniProt 23186163
S893 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S925 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S929 Phosphorylation PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
K944 Ubiquitination PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
Y970 Phosphorylation PhosphoSitePlus
S995 Phosphorylation PhosphoSitePlus
T1002 Phosphorylation PhosphoSitePlus
T1010 Phosphorylation IEDB 35494241
K1019 Ubiquitination PhosphoSitePlus
K1029 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046566 (hCARD11/Phos:1) pS559 PRO
PR:000046567 (hCARD11/Phos:2) pS559,pS652 PRO
PR:000046568 (hCARD11/Phos:3) pS559,pS644,pS652 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S116 P116 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S116 A116 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T117 P117 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T117 A117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y202 H202 Biomuta DOID:1324 / lung cancer [ cosmic ]
S433 T433 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S433 R433 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S433 G433 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S439 A439 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S439 F439 Biomuta DOID:4159 / skin cancer [ cosmic ]
S466 I466 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S466 G466 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S512 P512 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S512 F512 Biomuta DOID:4159 / skin cancer [ cosmic ]
T532 M532 Biomuta [ cosmic ] DOID:184 / bone cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S538 F538 Biomuta DOID:4159 / skin cancer [ cosmic ]
S559 C559 Biomuta DOID:1324 / lung cancer [ cosmic ]
S562 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S593 G593 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S593 N593 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S615 C615 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S615 F615 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S615 P615 Biomuta DOID:4159 / skin cancer [ cosmic ]
S644 T644 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S644 Y644 Biomuta DOID:363 / uterine cancer [ icgc ]
S652 L652 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T654 I654 Biomuta [ cosmic ]
Y751 H751 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T861 A861 Biomuta DOID:4159 / skin cancer [ cosmic ]
T861 I861 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T864 A864 Biomuta DOID:4159 / skin cancer [ cosmic ]
S893 C893 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S893 N893 Biomuta DOID:4159 / skin cancer [ cosmic ]
S925 N925 Biomuta DOID:4159 / skin cancer [ cosmic ]
S929 R929 Biomuta DOID:1324 / lung cancer [ cosmic ]
S929 I929 Biomuta DOID:1324 / lung cancer [ cosmic ]
K939 N939 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
Y970 C970 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y970 H970 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1002 P1002 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1010 K1010 Biomuta DOID:1324 / lung cancer [ cosmic ]