iPTMnet Report for Q9BXL6 (CARD14)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXL6 / CAR14_HUMAN
Protein Name Caspase recruitment domain-containing protein 14
Gene Name Name: CARD14
Synonyms:CARMA2;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXL6
DAG View
PRO Name caspase recruitment domain-containing protein 14 (human)
Definition A caspase recruitment domain-containing protein 14 that is encoded in the genome of human.
Short Label hCARD14
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXL6 (CARD14) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
S544 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18220336
S763 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
T944 Phosphorylation PhosphoSitePlus
S1002 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S241 C241 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S255 R255 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S276 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S276 L276 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S470 N470 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S544 A544 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S544 Y544 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1002 N1002 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]