iPTMnet Report for Q9BXI6 (TBC1D10A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXI6 / TB10A_HUMAN
Protein Name TBC1 domain family member 10A
Gene Name Name: TBC1D10A
Synonyms:EPI64,TBC1D10;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXI6
DAG View
PRO Name TBC1 domain family member 10A (human)
Definition A TBC1 domain family member 10A that is encoded in the genome of human.
Short Label hTBC1D10A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXI6 (TBC1D10A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
S39 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S40 Phosphorylation PhosphoSitePlus   UniProt 19690332
S43 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S45 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
Y226 Phosphorylation PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
Y328 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S407 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S409 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
R411 Methylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K433 Acetylation PhosphoSitePlus
K437 Acetylation PhosphoSitePlus
K440 Acetylation PhosphoSitePlus
K447 Acetylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation HPRD 18669648
S40 Phosphorylation HPRD 19413330
S43 Phosphorylation HPRD 19413330, 18669648
S407 Phosphorylation HPRD 18669648
S409 Phosphorylation HPRD 18669648, 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S40 C40 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S45 W45 Biomuta DOID:363 / uterine cancer [ icgc ]
K99 N99 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S338 I338 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
R411 C411 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
R411 H411 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S497 R497 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S500 C500 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S503 N503 Biomuta DOID:263 / kidney cancer [ cosmic ]