iPTMnet Report for Q9BXB1 (LGR4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BXB1 / LGR4_HUMAN
Protein Name Leucine-rich repeat-containing G-protein coupled receptor 4 precursor
Gene Name Name: LGR4
Synonyms:GPR48;
Organism Homo sapiens (Human)

PRO ID PR:Q9BXB1
DAG View
PRO Name leucine-rich repeat-containing G-protein coupled receptor 4 (human)
Definition A leucine-rich repeat-containing G-protein coupled receptor 4 that is encoded in the genome of human.
Short Label hLGR4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BXB1 (LGR4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N68 N-Glycosylation GlyGen   UniProt 23756652
K108 Acetylation PhosphoSitePlus
N199 N-Glycosylation GlyGen   UniProt 23756652
S332 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
N362 N-Glycosylation GlyGen 24190977
S616 Phosphorylation PhosphoSitePlus
Y848 Phosphorylation PhosphoSitePlus
K873 Ubiquitination PhosphoSitePlus
S880 Phosphorylation PhosphoSitePlus
Y908 Phosphorylation PhosphoSitePlus
S920 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y932 Phosphorylation PhosphoSitePlus
Y942 Phosphorylation PhosphoSitePlus
Y944 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S332 Phosphorylation HPRD 18452278
S333 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N199 T199 Biomuta DOID:3571 / liver cancer [ cosmic ]
S616 I616 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S880 N880 Biomuta DOID:4159 / skin cancer [ cosmic ]