iPTMnet Report for Q9BX95 (SGPP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BX95 / SGPP1_HUMAN
Protein Name Sphingosine-1-phosphate phosphatase 1
Gene Name Name: SGPP1
Synonyms:SPP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BX95
DAG View
PRO Name sphingosine-1-phosphate phosphatase 1 (human)
Definition A sphingosine-1-phosphate phosphatase 1 that is encoded in the genome of human.
Short Label hSGPP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BX95 (SGPP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K19 Ubiquitination PhosphoSitePlus
S101 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
S112 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17322306, 18220336, 18767875, 20058876, 18578522, 19007248, 19651622, 19664994, 18669648, 24275569, 18707149, 20166139, 18452278, 19415658, 20068231, 17081983
T114 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18767875, 18669648, 20068231
Y172 Phosphorylation PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K393 N393 Biomuta DOID:9256 / colorectal cancer [ cosmic ]