Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BX84 / TRPM6_HUMAN
Protein Name Transient receptor potential cation channel subfamily M member 6
Gene Name Name: TRPM6
Synonyms:CHAK2;
Organism Homo sapiens (Human)

PRO ID PR:Q9BX84
DAG View
PRO Name transient receptor potential cation channel subfamily M member 6 (human)
Definition A transient receptor potential cation channel subfamily M member 6 that is encoded in the genome of human.
Short Label hTRPM6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BX84 (TRPM6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K14 Methylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
Y519 Phosphorylation PhosphoSitePlus
S552 Phosphorylation RLIMS-P 28220887
S743 Phosphorylation PhosphoSitePlus
Y782 Phosphorylation PhosphoSitePlus
Y783 Phosphorylation PhosphoSitePlus
Y800 Phosphorylation PhosphoSitePlus
Y832 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation PhosphoSitePlus
K1144 Acetylation PhosphoSitePlus
K1145 Acetylation PhosphoSitePlus
S1244 Phosphorylation PhosphoSitePlus
T1245 Phosphorylation PhosphoSitePlus
T1304 Phosphorylation PhosphoSitePlus
T1430 Phosphorylation PhosphoSitePlus
T1435 Phosphorylation PhosphoSitePlus
S1563 Phosphorylation PhosphoSitePlus
S1747 Phosphorylation PhosphoSitePlus
S1756 Phosphorylation PhosphoSitePlus
T1851 Phosphorylation Q9BX84 (TRPM6) PhosphoSitePlus   RLIMS-P   UniProt 18490453, 18258429
Site PTM Type PTM Enzyme Score Source PMID
S1000 Phosphorylation HPRD 19664994


Q9BX84 (TRPM6) as PTM Enzyme



Substrate Site Score Source PMID
Q9BX84 (TRPM6) T1851 PhosphoSitePlus   UniProt 18258429


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K14 I14 Biomuta DOID:263 / kidney cancer [ cosmic ]
S78 C78 Biomuta DOID:1324 / lung cancer [ cosmic ]
T150 A150 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y519 * Biomuta DOID:3571 / liver cancer [ icgc ]
S743 Y743 Biomuta DOID:1324 / lung cancer [ tcga ]
S1000 L1000 Biomuta DOID:10283 / prostate cancer [ icgc ]
K1145 T1145 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T1245 A1245 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T1304 I1304 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1851 N1851 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]