iPTMnet Report for Q9BX84 (TRPM6)
Protein Information
| UniProt AC / UniProt ID | Q9BX84 / TRPM6_HUMAN |
| Protein Name | Transient receptor potential cation channel subfamily M member 6 |
| Gene Name | Name: TRPM6 Synonyms:CHAK2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BX84 |
| PRO Name | transient receptor potential cation channel subfamily M member 6 (human) |
| Definition | A transient receptor potential cation channel subfamily M member 6 that is encoded in the genome of human. |
| Short Label | hTRPM6 |
| Category | organism-gene |
DAG ViewQ9BX84 (TRPM6) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K14 | Methylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T509 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y519 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S552 | Phosphorylation | score0 | RLIMS-P | 28220887 | ||
| S743 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y782 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y783 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y800 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y832 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1000 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1144 | Acetylation | score1 | PhosphoSitePlus | |||
| K1145 | Acetylation | score1 | PhosphoSitePlus | |||
| S1244 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1430 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1563 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1747 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1756 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1851 | Phosphorylation | Q9BX84 (TRPM6) | score4 | PhosphoSitePlus RLIMS-P Signor UniProt | 18490453, 18258429 |
Q9BX84 (TRPM6) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| Q9BX84 (TRPM6) | T1851 | score3 | PhosphoSitePlus Signor UniProt | 18258429 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K14 | I14 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| S78 | C78 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T150 | A150 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y519 | D519 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S743 | Y743 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y782 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T1245 | A1245 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T1304 | I1304 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T1851 | N1851 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
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