iPTMnet Report for Q9BX26 (SYCP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BX26 / SYCP2_HUMAN
Protein Name Synaptonemal complex protein 2
Gene Name Name: SYCP2
Synonyms:SCP2;
Organism Homo sapiens (Human)

PRO ID PR:Q9BX26
DAG View
PRO Name synaptonemal complex protein 2 (human)
Definition A synaptonemal complex protein 2 that is encoded in the genome of human.
Short Label hSYCP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BX26 (SYCP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K357 Acetylation PhosphoSitePlus
K361 Acetylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
T470 Phosphorylation HPRD 17322306
S478 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
T501 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
Y966 Phosphorylation PhosphoSitePlus
S967 Phosphorylation PhosphoSitePlus
K992 Acetylation PhosphoSitePlus
T1019 Phosphorylation PhosphoSitePlus
T1021 Phosphorylation PhosphoSitePlus
S1040 Phosphorylation PhosphoSitePlus
S1042 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus
T1060 Phosphorylation PhosphoSitePlus
K1065 Acetylation PhosphoSitePlus
K1066 Acetylation PhosphoSitePlus
S1110 Phosphorylation PhosphoSitePlus
S1111 Phosphorylation PhosphoSitePlus
Y1130 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
Y1140 Phosphorylation PhosphoSitePlus
Y1241 Phosphorylation PhosphoSitePlus
S1249 Phosphorylation PhosphoSitePlus
S1253 Phosphorylation PhosphoSitePlus
S1254 Phosphorylation PhosphoSitePlus
S1256 Phosphorylation PhosphoSitePlus
S1523 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S481 L481 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S502 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S543 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S543 L543 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K681 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K992 Q992 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1056 F1056 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1060 M1060 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1066 T1066 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1138 L1138 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic, icgc ]
Y1241 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1249 N1249 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1254 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1256 Y1256 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S1256 C1256 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]