iPTMnet Report for Q9BWW4 (SSBP3)
Protein Information
| UniProt AC / UniProt ID | Q9BWW4 / SSBP3_HUMAN |
| Protein Name | Single-stranded DNA-binding protein 3 |
| Gene Name | Name: SSBP3 Synonyms:SSDP,SSDP1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BWW4 |
| PRO Name | single-stranded DNA-binding protein 3 (human) |
| Definition | A single-stranded DNA-binding protein 3 that is encoded in the genome of human. |
| Short Label | hSSBP3 |
| Category | organism-gene |
Q9BWW4 (SSBP3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K6 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y23 | Phosphorylation | P06239 (LCK) | score3 | PhosphoSitePlus RLIMS-P | 18080319 | |
| Y25 | Phosphorylation | P06239 (LCK) | score3 | PhosphoSitePlus RLIMS-P | 18080319 | |
| R155 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| R161 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| R165 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| R202 | Methylation | score1 | PhosphoSitePlus | |||
| T265 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928, 35254053 | ||
| S347 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928, 35254053 | ||
| S347 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18220336, ... | ||
| S352 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 19690332 | ||
| S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T360 | Phosphorylation | P28482 (MAPK1) | score2 | neXtProt phospho.ELM PhosphoSitePlus UniProt | 22028470, 23186163, 18220336, ... | |
| S381 | O-Glycosylation | score1 | GlyGen | 29485866, 29351928, 35254053 | ||
| S381 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 | ||
| T385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S387 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S347 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 19664994, ... | ||
| S352 | Phosphorylation | score0 | HPRD | 19413330 | ||
| T360 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 | ||
| S381 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S387 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| R128 | Methylation | score1 | PhosphoSitePlus | |||
| S320 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 19664994, ... | ||
| S325 | Phosphorylation | score0 | HPRD | 19413330 | ||
| T333 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 | ||
| S354 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S360 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S327 | Phosphorylation | score0 | HPRD | 19413330, 17322306, 19664994, ... | ||
| S332 | Phosphorylation | score0 | HPRD | 19413330 | ||
| T340 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 | ||
| S361 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S367 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R128 | Q128 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| R128 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S320 | Y320 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S320 | C320 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S327 | C327 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S327 | Y327 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S354 | Y354 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S361 | Y361 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View