iPTMnet Report for Q9BWT1 (CDCA7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BWT1 / CDCA7_HUMAN
Protein Name Cell division cycle-associated protein 7
Gene Name Name: CDCA7
Synonyms:JPO1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BWT1
DAG View
PRO Name cell division cycle-associated protein 7 (human)
Definition A cell division cycle-associated protein 7 that is encoded in the genome of human.
Short Label hCDCA7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BWT1 (CDCA7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Acetylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
K75 Sumoylation PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
T81 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K131 Sumoylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus   UniProt 23186163
S152 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor   UniProt 23166294, 23186163
T163 Phosphorylation P31749 (AKT1) PhosphoSitePlus   Signor 23166294
S190 Phosphorylation PhosphoSitePlus   UniProt 21406692
K204 Ubiquitination PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
Y359 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K364 Sumoylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9BWT1 (CDCA7) T163 P01106 (MYC) unknown eFIP 23166294


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S104 F104 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S110 R110 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K126 Q126 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S142 L142 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
Y205 H205 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T213 I213 Biomuta DOID:4159 / skin cancer [ cosmic ]