iPTMnet Report for Q9BWH2 (FUNDC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BWH2 / FUND2_HUMAN
Protein Name FUN14 domain-containing protein 2
Gene Name Name: FUNDC2
Synonyms:HCBP6;ORFNames:DC44,HCC3,PD03104;
Organism Homo sapiens (Human)

PRO ID PR:Q9BWH2
DAG View
PRO Name FUN14 domain-containing protein 2 (human)
Definition A FUN14 domain-containing protein 2 that is encoded in the genome of human.
Short Label hFUNDC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BWH2 (FUNDC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus   UniProt 23186163
T16 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus   UniProt 24275569
K62 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
S151 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18767875, 18578522, 19651622, 24275569, 20166139, 19690332
K161 Ubiquitination PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K68 T68 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K150 N150 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S151 I151 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S167 L167 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]