iPTMnet Report for Q9BWF2 (TRAIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BWF2 / TRAIP_HUMAN
Protein Name E3 ubiquitin-protein ligase TRAIP
Gene Name Name: TRAIP
Synonyms:RNF206;
Organism Homo sapiens (Human)

PRO ID PR:Q9BWF2
DAG View
PRO Name E3 ubiquitin-protein ligase TRAIP (human)
Definition An E3 ubiquitin-protein ligase TRAIP that is encoded in the genome of human.
Short Label hTRAIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BWF2 (TRAIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C25 Methylation IEDB 31844290
K80 Sumoylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
K127 Sumoylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K205 Sumoylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
K247 Sumoylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
S259 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340
S266 O-Glycosylation GlyGen 30379171
S295 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
K453 Sumoylation PhosphoSitePlus
T454 O-Glycosylation GlyGen 30379171
K462 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K80 N80 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T117 I117 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K127 N127 Biomuta DOID:1324 / lung cancer [ cosmic ]
K205 N205 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K362 E362 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K453 N453 Biomuta DOID:5041 / esophageal cancer [ cosmic ]