iPTMnet Report for Q9BWE0 (REPIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BWE0 / REPI1_HUMAN
Protein Name Replication initiator 1
Gene Name Name: REPIN1
Synonyms:RIP60,ZNF464;
Organism Homo sapiens (Human)

PRO ID PR:Q9BWE0
DAG View
PRO Name replication initiator 1 (human)
Definition A replication initiator 1 that is encoded in the genome of human.
Short Label hREPIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BWE0 (REPIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S27 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
T30 Phosphorylation PhosphoSitePlus   UniProt 23186163
K33 Acetylation PhosphoSitePlus   UniProt 19608861
K33 Ubiquitination PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
K276 Acetylation PhosphoSitePlus   UniProt 19608861
T287 Phosphorylation PhosphoSitePlus
S329 Phosphorylation HPRD   PhosphoSitePlus 19651622
T398 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
T510 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 18691976, 18669648, 20068231
S329 Phosphorylation HPRD 19651622
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S21 C21 Biomuta DOID:1319 / brain cancer [ cosmic ]
S24 F24 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S27 L27 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K276 N276 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T398 I398 Biomuta DOID:4159 / skin cancer [ cosmic ]
S500 F500 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T510 M510 Biomuta DOID:263 / kidney cancer [ cosmic ]