iPTMnet Report for Q9BW71 (HIRIP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BW71 / HIRP3_HUMAN
Protein Name HIRA-interacting protein 3
Gene Name Name: HIRIP3
Organism Homo sapiens (Human)

PRO ID PR:Q9BW71
DAG View
PRO Name HIRA-interacting protein 3 (human)
Definition A HIRA-interacting protein 3 that is encoded in the genome of human.
Short Label hHIRIP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BW71 (HIRIP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
K47 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
T84 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243, 17081983
S87 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243, 17081983
S98 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S100 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S102 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935, 17081983
S104 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S107 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S108 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
Y111 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S125 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...15302935, 18669648, 23186163, 19690332, 20068231
S136 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S142 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S143 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
S159 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 20068231, 17081983
S160 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...18669648, 20068231, 17081983
K179 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
S188 O-Glycosylation GlyGen 30379171, 31492838
S196 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 17287340, ...16964243, 18669648, 23186163, 19690332, 20068231, 17081983
S199 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 23186163, ...17081983, 15302935, 18669648, 17287340, 20068231, 16964243
T207 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S223 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...15302935, 18669648, 23186163, 19690332
S227 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...15302935, 18669648, 17287340, 19690332, 20068231, 17081983
S269 Phosphorylation PhosphoSitePlus
S289 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S291 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S300 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S301 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S305 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S317 Phosphorylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
S330 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 18669648, ...23186163, 20068231
S332 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 18669648, ...23186163, 20068231
S333 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...17287340, 20068231
S339 Phosphorylation PhosphoSitePlus
S357 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
T358 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S359 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S363 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S370 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...15302935, 18669648, 17081983
S372 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S399 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K469 Acetylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
T471 Phosphorylation PhosphoSitePlus   UniProt 23186163
S473 Phosphorylation PhosphoSitePlus
K476 Acetylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
C477 Methylation IEDB 31844290
S492 Phosphorylation PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
T527 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus   UniProt 23186163
S543 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus   UniProt 20068231
S551 Phosphorylation PhosphoSitePlus   UniProt 20068231
S555 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
Site PTM Type PTM Enzyme Score Source PMID
S27 Phosphorylation HPRD 20068231
T84 Phosphorylation HPRD 19413330, 18669648, 18212344, ...19415658, 17081983
S87 Phosphorylation HPRD 19413330, 17081983, 18669648, ...19415658, 16964243
S98 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S100 Phosphorylation HPRD 18669648, 17081983, 18452278
S102 Phosphorylation HPRD 19651622, 15302935, 18452278
S104 Phosphorylation HPRD 18669648, 17081983, 18452278
S107 Phosphorylation HPRD 17081983, 18452278
S108 Phosphorylation HPRD 18452278
Y111 Phosphorylation HPRD 17081983
S125 Phosphorylation HPRD 19413330, 17322306, 17287340, ...19664995, 18452278, 19651622, 18669648, 20068231
S136 Phosphorylation HPRD 17287340
S142 Phosphorylation HPRD 19651622, 17081983, 20068231
S143 Phosphorylation HPRD 19651622, 17081983, 20068231
S159 Phosphorylation HPRD 19651622, 18669648, 16964243, ...20068231, 17081983
S160 Phosphorylation HPRD 17081983, 19651622, 18669648, ...17693683, 20068231, 16964243
Y167 Phosphorylation HPRD 17693683
S196 Phosphorylation HPRD 19413330, 16083285, 17287340, ...16964243, 18452278, 19651622, 18669648, 20068231, 18212344
S199 Phosphorylation HPRD 17287340, 16964243, 15302935, ...19651622, 18669648, 20068231, 18212344
S219 Phosphorylation HPRD 19413330, 20068231
S223 Phosphorylation HPRD 19413330, 17287340, 18767875, ...15302935, 18452278, 19651622, 19664994, 18669648
S227 Phosphorylation HPRD 19413330, 17322306, 17287340, ...16964243, 18767875, 19664994, 18452278, 19651622, 18669648, 20068231
S289 Phosphorylation HPRD 17322306, 19413330, 19651622, ...20068231
S291 Phosphorylation HPRD 17322306, 19413330, 19651622, ...20068231
S300 Phosphorylation HPRD 19651622, 17287340
S301 Phosphorylation HPRD 19651622, 17287340
S305 Phosphorylation HPRD 17322306, 19651622, 17287340
S330 Phosphorylation HPRD 19651622, 18669648, 17287340, ...20068231
S332 Phosphorylation HPRD 19651622, 18669648, 17287340, ...20068231
S333 Phosphorylation HPRD 19651622, 18669648, 17287340, ...20068231
S357 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
T358 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S359 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S363 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S370 Phosphorylation HPRD 19651622, 18669648, 15302935, ...16964243, 20068231
S372 Phosphorylation HPRD 19651622, 18669648, 17081983
T471 Phosphorylation HPRD 20068231
S530 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S550 Phosphorylation HPRD 19651622, 20068231
S551 Phosphorylation HPRD 19651622, 20068231
S555 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 E5 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S87 G87 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S100 L100 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S136 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S196 N196 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S223 R223 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S223 N223 Biomuta [ cosmic ]
S291 I291 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K324 E324 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S399 Y399 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S400 C400 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
C477 Y477 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T509 A509 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T527 A527 Biomuta DOID:1793 / pancreatic cancer [ icgc ]