iPTMnet Report for Q9BVT8 (TMUB1)
Protein Information
| UniProt AC / UniProt ID | Q9BVT8 / TMUB1_HUMAN |
| Protein Name | Transmembrane and ubiquitin-like domain-containing protein 1 |
| Gene Name | Name: TMUB1 Synonyms:C7orf21,DULP,HOPS;ORFNames:SB144,UNQ763/PRO1555; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BVT8 |
| PRO Name | transmembrane and ubiquitin-like domain-containing protein 1 (human) |
| Definition | A transmembrane and ubiquitin-like domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hTMUB1 |
| Category | organism-gene |
Q9BVT8 (TMUB1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T71 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
| S73 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| R77 | Methylation | score1 | PhosphoSitePlus | |||
| T87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T90 | O-Glycosylation | score1 | GlyGen | 32938750 | ||
| T92 | O-Glycosylation | score1 | GlyGen | 30459171, 32938750 | ||
| T92 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18691976, 18669648, 20068231 | ||
| S98 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18691976, 18669648, 20068231 | ||
| K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N111 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T124 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S127 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K129 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S73 | R73 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| R77 | K77 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S98 | C98 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |
DAG View