iPTMnet Report for Q9BVQ7 (AFG2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BVQ7 / AFG2B_HUMAN
Protein Name ATPase family gene 2 protein homolog B
Gene Name Name: AFG2B
Synonyms:SPATA5L1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BVQ7
DAG View
PRO Name ribosome biogenesis protein SPATA5L1 (human)
Definition A ribosome biogenesis protein SPATA5L1 that is encoded in the genome of human.
Short Label hSPATA5L1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BVQ7 (AFG2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S5 Phosphorylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
C57 Methylation IEDB 31844290
S80 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
K372 Acetylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K375 Acetylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K727 Ubiquitination PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus
Y738 Phosphorylation PhosphoSitePlus
K743 Sumoylation PhosphoSitePlus
K743 Ubiquitination PhosphoSitePlus
K744 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S5 L5 Biomuta DOID:1324 / lung cancer [ cosmic ]
K499 N499 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K499 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S607 R607 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S610 I610 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K733 N733 Biomuta DOID:9256 / colorectal cancer [ cosmic ]