iPTMnet Report for Q9BVP2 (GNL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BVP2 / GNL3_HUMAN
Protein Name Guanine nucleotide-binding protein-like 3
Gene Name Name: GNL3
Synonyms:E2IG3,NS;
Organism Homo sapiens (Human)

PRO ID PR:Q9BVP2
DAG View
PRO Name guanine nucleotide-binding protein-like 3 (human)
Definition A guanine nucleotide-binding protein-like 3 that is encoded in the genome of human.
Short Label hGNL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BVP2 (GNL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K17 Acetylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus   UniProt 19608861
K99 Sumoylation PhosphoSitePlus
K114 Sumoylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
C156 Methylation IEDB 31844290
S168 Phosphorylation IEDB 35494241
K171 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
S207 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...34019948, 35083852, 28510447, 33465208
K224 Methylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
R230 Methylation PhosphoSitePlus
C234 Methylation IEDB 31844290
K237 Acetylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
K275 Sumoylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
T289 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
T366 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K388 Sumoylation PhosphoSitePlus
C403 Methylation IEDB 31844290
K434 Ubiquitination PhosphoSitePlus
K444 Sumoylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus   UniProt 24275569
T494 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus   UniProt 24275569
S529 Phosphorylation PhosphoSitePlus   UniProt 19690332
K534 Sumoylation PhosphoSitePlus
Y542 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
Y548 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T250 Phosphorylation HPRD 20068231
S273 Phosphorylation HPRD 20068231
S490 Phosphorylation HPRD 18452278
T494 Phosphorylation HPRD 18452278
S529 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T238 Phosphorylation HPRD 20068231
S261 Phosphorylation HPRD 20068231
S478 Phosphorylation HPRD 18452278
T482 Phosphorylation HPRD 18452278
S517 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K46 R46 Biomuta DOID:184 / bone cancer [ cosmic ]
K179 T179 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K185 M185 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K185 N185 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K197 N197 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
C403 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]