iPTMnet Report for Q9BVL2 (NUP58)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BVL2 / NUP58_HUMAN
Protein Name Nucleoporin p58/p45
Gene Name Name: NUP58
Synonyms:KIAA0410,NUPL1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BVL2
DAG View
PRO Name nucleoporin p58/p45 (human)
Definition A nucleoporin p58/p45 that is encoded in the genome of human.
Short Label hNUP58
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BVL2 (NUP58) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T11 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S14 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T15 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T22 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S23 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S49 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T50 O-Glycosylation GlyGen 29351928
S51 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T52 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T55 O-Glycosylation GlyGen 29351928
T56 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S57 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S60 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S61 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T88 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T90 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T94 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T97 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T100 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T101 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S102 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T105 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T106 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S109 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T120 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T127 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S128 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T129 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S130 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S132 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T141 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S142 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T143 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S147 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T148 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T201 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T205 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T208 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S209 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T210 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
K240 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
T331 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
Y339 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
T445 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T445 Phosphorylation PhosphoSitePlus
T449 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T450 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T453 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T471 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T478 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S483 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S487 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T490 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S522 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T523 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T561 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S563 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
T567 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
S571 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...30397120, 34725712, 21740066, 29351928, 34019948, 32870666, 20305658, 32119511, 21300897, 22121020, 35289036
Site PTM Type PTM Enzyme Score Source PMID
T331 Phosphorylation HPRD 19651622, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T319 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 P6 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T88 I88 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T90 S90 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T97 M97 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T100 S100 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S102 P102 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T105 A105 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T129 A129 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T210 S210 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K310 N310 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K330 M330 Biomuta DOID:3571 / liver cancer [ cosmic ]
T567 I567 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]