Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BVC5 / ASHWN_HUMAN
Protein Name Ashwin
Gene Name Name: C2orf49
Organism Homo sapiens (Human)

PRO ID PR:Q9BVC5
DAG View
PRO Name ashwin (human)
Definition An ashwin that is encoded in the genome of human.
Short Label hC2orf49
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BVC5 (C2orf49) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus   UniProt 23186163
S143 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S145 Phosphorylation PhosphoSitePlus
S146 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S147 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S148 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S155 Phosphorylation phospho.ELM 18669648
S182 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S184 Phosphorylation PhosphoSitePlus   UniProt 23186163
S189 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 17287340, 19690332, 20068231
S193 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18847512, ...18669648, 24275569, 17287340, 19690332, 20068231
S193 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T197 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18847512, 18669648, ...17287340, 19690332, 20068231
T197 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T198 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...18847512
T198 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
K201 Acetylation PhosphoSitePlus
K218 Acetylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S143 Phosphorylation HPRD 18669648, 20068231
S145 Phosphorylation HPRD 19413330
S146 Phosphorylation HPRD 18669648
S147 Phosphorylation HPRD 18669648
S155 Phosphorylation HPRD 18669648
T178 Phosphorylation HPRD 20068231
S182 Phosphorylation HPRD 20068231
S184 Phosphorylation HPRD 20058876, 20068231
S189 Phosphorylation HPRD 17287340, 17081983, 18767875, ...20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 20068231
S193 Phosphorylation HPRD 19413330, 17287340, 17081983, ...18767875, 18452278, 19651622, 18669648, 18707149, 20068231
T197 Phosphorylation HPRD 19413330, 17287340, 19664995, ...19651622, 18669648, 20068231
T198 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S147 L147 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S147 W147 Biomuta DOID:1324 / lung cancer [ cosmic ]
S148 N148 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T178 M178 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S182 R182 Biomuta DOID:184 / bone cancer [ cosmic ]
S184 L184 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S189 L189 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]