iPTMnet Report for Q9BVC5 (C2orf49)
Protein Information
UniProt AC / UniProt ID | Q9BVC5 / ASHWN_HUMAN |
Protein Name | Ashwin |
Gene Name | Name: C2orf49 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BVC5 |
PRO Name | ashwin (human) |
Definition | An ashwin that is encoded in the genome of human. |
Short Label | hC2orf49 |
Category | organism-gene |
Q9BVC5 (C2orf49) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
S112 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S143 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S145 | Phosphorylation | score1 | PhosphoSitePlus | |||
S146 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S147 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
S155 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S182 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332 | ||
S184 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S189 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 17081983, ... | ||
S193 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983, 18847512, ... | ||
S193 | Phosphorylation | P24941 (CDK2) | score1 | PhosphoSitePlus | 18847512 | |
T197 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 18847512, 18669648, ... | ||
T197 | Phosphorylation | P24941 (CDK2) | score1 | PhosphoSitePlus | 18847512 | |
T198 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332, ... | ||
T198 | Phosphorylation | P24941 (CDK2) | score1 | PhosphoSitePlus | 18847512 | |
K201 | Acetylation | score1 | PhosphoSitePlus | |||
K218 | Acetylation | score1 | PhosphoSitePlus | |||
T230 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S143 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S145 | Phosphorylation | score0 | HPRD | 19413330 | ||
S146 | Phosphorylation | score0 | HPRD | 18669648 | ||
S147 | Phosphorylation | score0 | HPRD | 18669648 | ||
S155 | Phosphorylation | score0 | HPRD | 18669648 | ||
T178 | Phosphorylation | score0 | HPRD | 20068231 | ||
S182 | Phosphorylation | score0 | HPRD | 20068231 | ||
S184 | Phosphorylation | score0 | HPRD | 20058876, 20068231 | ||
S189 | Phosphorylation | score0 | HPRD | 17287340, 17081983, 18767875, ... | ||
S193 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 17081983, ... | ||
T197 | Phosphorylation | score0 | HPRD | 19413330, 17287340, 19664995, ... | ||
T198 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S147 | L147 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S147 | W147 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S148 | N148 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
T178 | M178 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
S182 | R182 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
S184 | L184 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S189 | L189 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] |